Tag: PCOS

Thinking about egg freezing? Learn how it works, success rates, costs, and when to start preserving your fertility. Thinking about freezing your eggs? Whether you’re planning for the future or not ready to start a family just yet, egg freezing  is a powerful fertility preservation option. In this guide, we’ll walk you through everything you need to know about how to freeze your eggs, how to freeze your eggs, and what factors to consider, including age, success rates, and costs. What Is Egg Freezing and Why Do People Do It? Egg freezing, also known as oocyte cryopreservation, is a fertility preservation technique that allows you to save your eggs for future use. It’s becoming an increasingly popular option for those who want to keep their options open when it comes to having children later in life – but does it guarantee you’ll have a baby? Let’s explore the facts. People choose egg freezing for a variety of reasons, including: Planning to have children later in life Undergoing medical treatment that could affect fertility (e.g. chemotherapy) Personal or career goals Not having found the right partner yet We explore this further in Who should consider fertility preservation?  How Does Egg Freezing Work? Step 1: Hormone Stimulation You’ll take fertility medications to stimulate your ovaries to produce multiple mature eggs in one cycle. During this time, you’ll attend regular scans and blood tests to monitor your response. Step 2: Egg Collection (Egg Retrieval) After ~10-14 days of stimulation, your eggs are collected in a short medical procedure under sedation. Once your eggs are ready, they’ll be collected via a minor surgical procedure under sedation. Most people recover within a day or two. Step 3: Freezing and Storage (Cryopreservation) Your eggs are frozen using a fast-freezing technique called vitrification, then stored safely in liquid nitrogen for potential use in the future. Can Freezing Your Eggs Guarantee a Baby? The short answer is no – freezing your eggs does not guarantee you’ll have a baby. It can increase your chances, especially if you freeze your eggs at a younger age, but several factors affect whether you’ll conceive and carry a baby successfully later in life. One major factor is your age at the time of freezing. Younger eggs tend to be healthier and more likely to result in a successful pregnancy. Freezing eggs in your twenties or early thirties typically leads to better outcomes than doing so in your late thirties or forties. Another key factor is the number of eggs you freeze. Not all eggs will survive the freezing and thawing process. Even if they do, not every egg will fertilise or become a healthy embryo. Your overall reproductive health at the time you want to use the eggs also matters. This includes the health of your uterus, your hormone levels, and any underlying fertility issues that may have developed over time. Success also depends on the quality of sperm used and the effectiveness of IVF when you’re ready to conceive. A partner’s or donor’s sperm must be healthy enough to fertilise the eggs, and the embryo must implant successfully in the uterus. When Is the Best Age to Freeze Eggs? If you’re asking, “When should I freeze my eggs?” the general recommendation from fertility experts is between you late 20s to mid 30s. During this window, egg quality and ovarian reserve are still relatively high, giving you the best chance of success later. But this isn’t a one-size-fits-all decision. Everyone’s fertility journey is different. Some people may choose to free their eggs earlier or later depending on their health, family history, a medical condition that could affect fertility, or plans to undergo treatments like chemotherapy. Others may freeze their eggs later due to career, relationship, or financial considerations.. While it’s still possible to freeze your eggs after 35, it’s important to know that success rates may decline as egg quality and reserve begin to drop with age. If you’re wondering when to start the process, the best first step is to book a fertility assessment. This typically includes hormone testing and an ultrasound to check your ovarian reserve. With this information, you can get a clearer picture of your fertility status and make an empowered decision about whether and when to freeze your eggs. You may also want to understand how ageing can affect fertility rates in women. How Many Eggs Do I Need To Freeze to Have a Baby? There’s no magic number, but we can estimate based on age and clinical data. Based on research from studies like Goldman et al. (2017) and Doyle et al. (2016), we can estimate the number of mature eggs typically needed to have about a 70% chance of achieving one full-term pregnancy. These numbers are estimates based on aiming for one baby, so if you’re hoping to grow a bigger family, freezing more eggs may be necessary to maximise your chances.   Note: These numbers aim for one full-term pregnancy. This estimation may vary depending on other factors. If the goal is more than one child, more eggs should be frozen. What Are the Egg Freezing Success Rates? If you’re thinking about freezing your eggs, one of the most important things to understand is your chance of having a baby later on. While there’s no guaranteed number of eggs that will result in a full-term pregnancy, we can give a reliable estimate based on several factors especially your age at the time of freezing. Success with frozen eggs depends on four key steps: egg survival after thawing, fertilisation, embryo development, and successful implantation. Let’s break it down. Age at the Time of Freezing Matters Most Age is the single biggest factor influencing the quality and quantity of eggs. Younger eggs tend to be healthier and have a much higher chance of leading to a successful pregnancy. How Well Do Eggs Survive Freezing and Thawing? Thanks to modern vitrification techniques, between 90–95% of mature eggs survive the thawing process. That’s a big leap from […]

As a consultant dermatologist, I’ve seen many women come through my clinic doors frustrated by stubborn acne that doesn’t seem to respond to any treatment. If this sounds familiar, you’re not alone. Acne can be a visible and sometimes painful marker of an underlying condition called polycystic ovary syndrome (PCOS). Understanding the connection between acne and PCOS is crucial, not just for the health of your skin but for your overall well being Why Should You Consider PCOS if You Have Acne? Acne is often thought of as a teenage problem, something that magically disappears with age. But for many people, particularly those with PCOS, acne can persist into adulthood and become a significant concern. PCOS is a hormonal condition that affects up to 10% of women and people assigned female at birth and is often characterised by elevated levels of androgens like testosterone– hormones that can lead to increased oil production in the skin, causing clogged pores and, subsequently, acne. But it’s not just any acne we’re talking about. Women with PCOS often experience more persistent and inflammatory acne that tends to appear along the lower third of the face, jawline, and upper neck. This is because of the hormonal imbalance that’s driving excess oil production. So, if you find yourself struggling with acne in these areas and have tried countless treatments without success, it might be time to think beyond the skincare aisle and look a little deeper. What Are the Signs That PCOS Could Be Affecting Your Skin? When we talk about PCOS and acne, it’s essential to consider the bigger picture. PCOS is not just about your skin; it can impact various aspects of your health. So, when should you start thinking about getting screened for PCOS? Here are a few signs that might suggest PCOS could be contributing to your acne: If you’re noticing any of these symptoms alongside your acne, it’s worth discussing them with your doctor. Why Early Diagnosis and Treatment is Key If you’ve been diagnosed with PCOS, it can feel like a lot to take in. But remember, getting an early diagnosis is a positive step. Why? Because it allows you to take control of your health and manage the condition effectively. PCOS doesn’t just affect your skin; it’s a systemic condition that can have long-term health implications, including an increased risk of developing type 2 diabetes, high blood pressure, mental health issues and other metabolic issues. It can also impact fertility and increase the risk of complications during pregnancy. By diagnosing PCOS early, you can work with your healthcare provider to develop a management plan tailored to your needs. This might include lifestyle changes, like a balanced diet and regular exercise, which are crucial in managing weight and improving insulin sensitivity – both key factors in PCOS. Medications may also be prescribed to help regulate your menstrual cycle, manage acne, or reduce excess hair growth. Treating Acne in PCOS: What Works? When it comes to managing acne in the context of PCOS, it’s not just about what you put on your skin – it’s also about addressing the hormonal imbalance driving it. Here are some treatment options that might be recommended: Lifestyle Changes: Small Steps, Big Impact Don’t underestimate the power of lifestyle changes when managing PCOS and its symptoms. Maintaining a healthy weight through a balanced diet and regular physical activity can significantly impact hormone levels and insulin sensitivity, improving both your skin and overall health. Focus on whole foods, such as fruits, vegetables, lean proteins, and whole grains, and try to reduce your intake of sugar and processed foods. Staying hydrated and getting plenty of sleep can also make a difference. In addition to lifestyle changes, a consistent and gentle skincare routine can help manage acne. Opt for non-comedogenic (non-pore-clogging) products and avoid harsh scrubs or overly drying treatments that can irritate the skin further. Take Charge of Your Health Remember, PCOS is a manageable condition. With the right care and support, you can control its impact on your life. Getting screened is the first step towards understanding your body better and finding a treatment plan that works for you.PCOS and acne don’t have to define you. With early screening and proper management, you can take control of your skin and health and feel more confident in your body. The journey might seem daunting, but with the right information and a proactive approach, you can find a way forward that brings clarity and comfort to both your skin and your overall well being Inspiring skin confidence with Hertility and Self London Hertility and Self London are collaborating to give you absolute clarity into what’s going on inside your body and inspire skin confidence. We’re working with patients to uncover how hormones impact not only our reproductive health but also our skin’s natural glow.Discover the partnership

COVID-19 and the shift to remote working has catalysed the demand for mental health benefits – it is now a “must have” for employers in 2021. In fact, in a recent survey, 91% of respondents stated that a company’s culture should support mental health. It is no coincidence that mental well-being is included in how reproductive health is defined by the World Health Organisation, stating that “Reproductive health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity, in all matters relating to the reproductive system and to its functions and processes”. These two elements of well-being are interconnected. As a result, it is impossible to provide comprehensive mental health benefits without considering the impact that reproductive health conditions can have and figuring out how employees dealing with those can be supported. How do reproductive health conditions affect mental health? InfertilityTake infertility, which affects 1 in 6 couples in the UK. Despite its prevalence, it is often met with confusion and denial.. This can seriously impact mental well-being – feelings of anxiety, depression and loss are all common. Besides, treatment can be time-consuming, stressful and a significant financial burden for individuals. Leading employers in the benefits space are recognising the impact that infertility may have on mental health and offering “fertility leave” as well as compassionate leave after miscarriage. EndometriosisReproductive health conditions such as endometriosis are associated with difficulty conceiving and chronic pain, both of which impact quality of life. Alongside having increased sick leave and loss of productivity, women with endometriosis feel their career goals were impacted negatively. Premenstrual syndrome (PMS)PMS describes the array of physical and emotional changes that occur as part of the monthly cycle. Approximately 90% of people who menstruate experience PMS. In some cases, this can be debilitating, a condition known as premenstrual dysphoric disorder (PMDD). PMDD can be so severe that suicidal thoughts are common in these women. Undiagnosed health issuesUnfortunately, it is not just the physical manifestations of the conditions alone that may impact employees’ mental health. Stigma and shame on reproductive health conditions from society and inadequate support from healthcare with symptom dismissal and months or years required to get to a diagnosis can be a significant cause of anxiety or depression for people suffering from a reproductive health condition. Many things in this journey even after getting the answers are outside of employees’ control. There are no guarantees that fertility treatments will succeed; failed attempts can seriously affect mental health, especially in those cases where little can be done to change the outcome. How can you support your employees on their reproductive health journey?There are several things that you can do to help alleviate the burden reproductive health conditions can place on mental health. Destigmatise reproductive health conditions by encouraging education and learning. This is a great way to challenge the current attitude to reproductive health conditions in the workplace and facilitates supportive conversations. Joining schemes provided by charitable bodies such as the Endometriosis Friendly Employer scheme can help you to make those first steps. Create a supportive workplace environment through flexible working hours for those who need to attend multiple appointments, inclusive leave policies and offering free menstrual products in bathrooms. Provide comprehensive reproductive health benefits by partnering with companies like Hertility to connect your employees to expert care and help them make informed decisions with regards to their reproductive health. These can include things such as proactive testing opportunities with actionable insights, fertility counselling, referrals to trusted clinics and specialist care with experts in the field. About Hertility HealthHertility Health is shaping the future of Reproductive Health by giving women the ability to understand and manage their fertility and hormone health from menstruation to menopause. 1 in 3 women suffer from a reproductive health issue, yet conversations around fertility, menopause and menstrual symptoms are still stigmatised in the workplace. As employees suffer in silence – up to £4k is lost per year per employee due to reduced productivity, absenteeism and presenteeism. Hertility reduces the need for unnecessary appointments and delay in diagnosis time through an online health assessment and at home test. To learn more about our Reproductive Health Education and Benefits for Employers, reach out to benefits@hertilityhealth.com or visit our website.

For many, the journey to parenthood can be a challenging process, both physically and emotionally. We’re here to help you understand the different causes of infertility, and the options available for those who need support. Quick facts: What is infertility? Infertility is defined as not being able to conceive after one year (or longer) of trying. This could be despite having regular unprotected sex with a partner, or trying using methods like artificial insemination (IUI).  There are 2 types of infertility: In the UK, as many as 1 in 7 heterosexual couples experience infertility, yet the causes are sometimes preventative, or treatable.  Causes of infertility  There can be many different reasons why you might struggle to conceive. This can include structural fertility issues, ovulation problems, underlying health conditions and hormonal imbalances. Let’s take a look at each. Ovulation issues  Anovulation, also known as the inability to ovulate, is the most common cause of infertility. Ovulation is when a mature egg is released from one of your ovaries, each month, during your menstrual cycle. The egg travels into the Fallopian tube, where it prepares to be fertilised by a sperm, before then travelling down the tube to the uterus.  When trying to conceive, ovulation is a crucial event, with the 5 days before ovulation and ovulation day itself often referred to as your ‘fertile window’.This is the time of the month when you’ll be most likely to get pregnant.  Research suggests that as many as 25% of infertility cases are caused by anovulation. Anovulation can be caused by: Another possible explanation is a problem with the egg maturation process. This means that an “immature” egg may be released from your ovaries when it is not quite ready and unable to fertilise. Underlying health conditions Polyendocrine Metabolic Ovary Syndrome (PMOS, formerly known as PCOS) PMOS is the most common underlying condition affecting fertility. PMOS affects as many as 1 in 10 people with ovaries.  People with PMOS produce higher levels of androgen hormones, like testosterone. This can disrupt your menstrual cycle, ovulation, and balance of cycling hormones—like oestrogen, follicle-stimulating hormone and luteinising hormone (LH). As PMOS is still under-researched and misunderstood, many people are left undiagnosed and are unaware they have it until they are actively trying to conceive. This is why it’s a good idea to check in on your hormones before you start your conception journey.  Primary ovarian insufficiency (POI)  POI is when the ovaries stop working properly before the age of 40. POI is far less common than PMOS, affecting only 1 in 100 women younger than 40. Your ovaries produce oestrogen and progesterone—two cycling hormones responsible for the regulation of your menstrual cycle. When their function is disrupted, ovulation can also become disrupted or stop completely.  People with POI also have a lower ovarian reserve, meaning fewer eggs for their age. Without a sufficient amount of eggs and the correct level of hormones needed to regulate your cycle, the possibility of conceiving is reduced considerably. According to the National Infertility Association, POI can be caused by genetics, autoimmune factors, induced by chemo or radiotherapy, or it can have an unknown cause. Uterine fibroids Uterine fibroids are noncancerous tumours that affect as many as 25% of people with a uterus. They can cause symptoms such as heavy periods, intermenstrual bleeding, and pelvic pain. In some cases, depending on the location in which they grow, and whether they affect the shape of the uterus or cervix, fibroids can also cause infertility.  This is because they can block the fallopian tubes, stopping eggs from meeting sperm, or reaching the uterus for implantation. They can also get in the way of implantation if they are near the inner lining of the womb.  Despite being less common than other causes of infertility, around 5-10% of infertile women and those assigned female-at-birth are found to have uterine fibroids, with their instance being much more common in Black women.  Endometriosis Endometriosis is a common reproductive health condition that affects around 1 in 10 women and people assigned female-at-birth. With endometriosis, tissue similar to the tissue that makes up the lining of the womb starts to grow in other places, such as the ovaries and the fallopian tubes, causing lesions and scarring.   This can cause several life-altering symptoms, such as painful and heavy periods, pain during or after intercourse and pelvic pain. It is also another common cause of infertility, with research suggesting it is present in around 20-50% of infertility cases. The exact link between endometriosis and infertility is unknown. However, some theories suggest that lesions and scarring can cause structural problems with the reproductive organs and chemical changes in the lining of the uterus. Structural infertility  Structural infertility is a problem with the anatomical structure of the reproductive organs. This can include blockages, structural damage or abnormal growth in the fallopian tubes, uterus or ovaries.  Structural issues with the ovaries or fallopian tubes can prevent eggs from being released from the ovaries or stop them from moving through the fallopian tubes to reach a sperm for fertilisation.   Additionally, if the structure of your uterus is abnormal or damaged, it may prevent eggs from implanting into the endometrium (uterus lining). This is needed to create a healthy embryo and pregnancy.  Structural infertility problems can also be caused by scarring from surgery, infections, injuries, or endometriosis.  Also, the growth of noncancerous tissues such as uterine polyps on the lining of the uterus, can cause blockages. Polyps occur when additional tissue grows on your uterus. However, sometimes tissue grows elsewhere in your reproductive system potentially blocking your fallopian tubes and preventing pregnancy.  Implantation failure Other possible explanations of implantation failure are: Infections and auto-immune disorders  Untreated sexually transmitted infections (STIs) may have serious consequences for your fertility. STIs like chlamydia or gonorrhoea can cause scarring and blocking of your Fallopian tubes.  Additionally, if syphilis is left to develop, it can cause stillbirth. There are also other forms of infections of the cervix with human papillomavirus (HPV) […]

Annie Coleridge, CEO of Alva Health, shares her story of getting a PMOS (formerly PCOS) and dermoid cyst diagnosis. Erratic periods I’ve always had a feeling something wasn’t quite right with my hormones. Nothing major, but something a little skew-whiff.  Since I was a teenager I’ve had erratic periods. They’re on the light side, making me one of the lucky ones, but sometimes they won’t come for months.  Once, just after my final exams at university, my period didn’t come for about 9 months. I’ve always been a normal weight and was eating ok (albeit a bit stressed about exams) but 9 months seemed excessive…  So did the endless doctor’s appointments checking that I wasn’t pregnant or having a flare of an autoimmune condition I had previously. That was my early 20s. My mid-twenties passed with little change to that pattern, to be honest. Months and months without a period, then they’d just restart again.  I tried to track my periods, but I didn’t have the monthly reminders to help me remember. So I just put up with a mild, low-level, background kind of anxiety about my reproductive health.  Weirdly, although I understand contraception pretty well, it made me reluctant to go on any hormonal birth control. I just didn’t want to mess with these hormones which seemed in such fine balance. And anyway, it didn’t bother me that much. Testing my hormones Then I started working at a health tech company, which really highlighted to me that knowledge is power when it comes to your body. Finally, it clicked – I really should check if my hormones are balanced.  I knew that wouldn’t hold all the answers to my period woes… but it seemed like a very interesting place to start.  When I got my first test back I had high testosterone and low oestrogen – which was not what I expected… I knew that raised testosterone suggested PMOS but I also knew I didn’t have the typical symptoms. Beyond the messed up periods and the raised testosterone, I just didn’t have much else that was typical for PMOS. Or at least I thought I didn’t.  What I knew about PMOS was that it usually causes heavy periods, excessive hair growth, insulin sensitivity and weight gain. I didn’t struggle with those. I had light, irregular periods and bad mood swings. But that was it.  So… I ignored my first few sets of results, for about a year. I’d had abnormally high cortisol results at the same time, so as ever I just sort of put it all down to stress. Maybe my periods were just super super super sensitive to stress. A sudden change Then my periods suddenly got incredibly heavy. I thought it might be a sign of something really serious so I went to a doctor. I don’t hate the doctors at all, but I do find the process often quite inconvenient. It just doesn’t fit in with my life. Despite having recent blood tests, the doctors made me take another test and told me I had PMOS. That was it. A single phone call. Just the test results and a simple conclusion. Nothing else on the matter,  no follow-up information.  Doctor Google and my mum (an actual doctor) helped me learn that there are loads of different types of PMOS. Turns out whilst some people get the more ‘classic’ PMOS symptoms it’s actually a hugely varied condition. PMOS diagnosis – what else? But this new diagnosis didn’t explain the sudden changes in my periods. Or at least I didn’t think it did. I was pretty confused to be honest. So I went back to my GP and they said I could have an ultrasound.  The process of finding out I had a dermoid cyst involved an initially inconclusive scan – where the sonographer simply told me that I had ‘some sort of mass.  Four weeks later, another scan followed. This time they told me that the mass was probably a ‘ benign cyst’. The probably in that sentence didn’t fill me with confidence. So I went to my GP to ask what next? What next was a very long wait to see an NHS gynaecologist.  Now, let me say that although I felt pretty horrific after my various appointments I am staunchly pro the NHS. They gave me a certain first diagnosis – PMOS – and a probable second one – a benign cyst.  I did feel a little lost though. Suddenly my fertility (not something I’d thought about being 28 years old at the time and in a very new relationship) felt uncertain. I’m not even sure I want kids but that feeling was very unsettling. Knowledge is power To get a quicker second diagnosis I went and got a private scan. I’m very lucky they could confirm it was a dermoid cyst that was not cancer.  They could also see the characteristic ‘string of pearls’ appearance around my ovaries that suggested PMOS. It was a relief to be able to see what was going on in my ovaries, although they didn’t look in the best shape I must say.  I feel so fortunate to have been able to quickly access answers but it took me years to take control of my reproductive health. Even though it’s not perfect – nothing ever is and it’s much better to know Written by Annie Coleridge, CEO Alva Health If like Annie, you’re experiencing irregular and erratic periods, it could be a sign of a hormonal imbalance. Our at-home hormone tests can help you get to the root of your period problems. Our team of experts include PMOS (formerly PCOS) specialists that can help you to manage your PMOS (formerly PCOS) symptoms.