Knowledge Centre

Research News: Fertility Preservation Outcome Study in Cancer Patients
21/09/2022/Bríd Ní Dhonnabháin
Recent research conducted by some of our Hertility Team, led by one of our co-founders Dr Natalie Getreu, has been published in the Fertility and Sterility Journal. Fertility can be affected by cancer and cancer treatment to such an extent that women may have reduced family planning options once they’ve completed their treatment. Although, records of the success of fertility preservation methods in cancer patients are not routinely collected by hospitals, fertility clinics or researchers. Instead, when it comes to egg and embryo freezing, clinicians routinely use success rates from patients that have undergone fertility preservation for social reasons as opposed to medical reasons. Therefore, our research team aimed to look into pregnancy outcomes in cancer survivors who had used their frozen tissues to provide more up-to-date and relevant information for these patients. Check your fertility The results revealed that between fertility preservation methods: egg, embryo or ovarian tissue freezing, there was no significant difference between these methods for women to have live births after pregnancies. At Hertility we are so proud to not only offer new and different care pathways for women but also to be home to so many amazing researchers. So we thought in this article we would take you through the research, and the findings and explain them to you. After all – knowledge is power! First up, let’s recap on fertility preservation…. We’ve already published an article that covers all the different types of fertility preservation for people with ovaries but here is a brief sum up: There are both medical and social reasons to undergo fertility preservation. Medical fertility preservation means preserving parts of your fertility in people who might lose their ability to reproduce due to upcoming medical treatment, for example, cancer patients about to undergo chemotherapy/radiotherapy or people undergoing gender reassignment surgery, or for some who have an autoimmune condition that want to protect their fertility. Whereas, social fertility preservation is when you are opting to freeze your eggs because of social and age-related factors. There are several different fertility preservation methods, some of which include: Egg freezing – This is what it says on the tin: collecting your egg cells and putting them on ice for later use. Embryo freezing – This process involves fertilising your collected egg with IVF using either donor’s or your partner’s sperm and then the resulting embryo is frozen until you are ready to use it. Ovarian tissue cryopreservation – This method is created mostly for younger patients who have not yet gone through puberty and are therefore not able to fully mature their egg cells. Tissue containing immature eggs is cut from their ovaries and is preserved in a tissue bank until the tissue can be re-implanted and used at a later stage, however, this is not routinely used for the general population. There are more fertility preservation options but in this study, researchers only included cancer patients who had undergone oocyte, embryo or ovarian tissue cryopreservation (freezing) What did this study do? Researchers followed cancer patients that had both fertility preservation and then had fertility-damaging cancer treatment (gonadotoxic therapy) who were now looking to start a family using their cryopreserved oocyte, embryo or ovarian tissue. The main outcomes this research looked at were if there were clinical pregnancies (clinical signs of the foetus can be either seen or heard), miscarriages (pregnancy loss) and live birth (completed pregnancies that result in a live birth). What were the results? This study found that between fertility preservation methods: egg, embryo or ovarian tissue freezing, there was no significant difference between these methods for women to have live births after pregnancies. (In science it’s all about whether a difference is significant or not!). Also high clinical pregnancy rates and live birth rates were observed in all techniques. They also found that freezing ovarian tissue results in significantly less miscarriages than embryo freezing, which is interesting and is something to further investigate! What do these results mean? Like anything in science, there are limitations in the study and this research does report some limitations since it was an early analysis. However, this is a really important and interesting starting point in this area of research and for cancer-related fertility preservation.Researchers hope that this study helps to establish better reporting of outcomes in cancer patients and will encourage clinicians to use appropriate statistics and information to counsel women who find themselves facing a cancer diagnosis on their chances of biological motherhood. If you fancy having a read of the article yourself, have a look here! At Hertility, we are dedicated to revolutionising women’s healthcare, whether that be through improving care pathways, helping women receive answers about their bodies through our at-home tests or contributing to the Women’s Health research. It’s all part of our mission for a #ReproductiveRevolution.

How do I know if I have normal AMH levels?
07/09/2022/Hertility
AMH (anti-Müllerian hormone) is a hormone made by the small, developing follicles in your ovaries. Measured with a simple blood test, and is a marker of your ovarian reserve or broadly, how many eggs you have left. It reflects egg quantity, not quality, and it’s one important piece of your wider fertility picture, not the whole story. If you’ve come across it while looking into your fertility, egg freezing, or “checking your egg count,” you’re in the right place. Here’s what AMH actually is, what your result can and can’t tell you. Quick facts: What is AMH? Anti-Müllerian hormone (AMH) is made by cells surrounding the small, developing follicles in your ovaries. Each of these follicles contains an immature egg. Because the number of these follicles is related to the size of your remaining egg pool, the amount of AMH in your blood can provide an indication of your ovarian reserve. Think of AMH as an indirect marker rather than an egg counter. It cannot tell you exactly how many eggs are left in your ovaries, but it can help show whether your ovarian reserve appears higher, lower or around what would be expected for your age. You’re born with all the eggs you’ll ever have, as we age, both our egg quality and quantity declines. As the pool shrinks, so does your AMH, which is what makes it such a useful window into where your reserve sits for your age. What is a normal AMH level for my age? There is no single normal AMH level that applies at every age. AMH naturally declines as you get older. A level that might be considered relatively low for someone in their 20s could be entirely expected for someone in their early 40s. That means the most useful question is not if you levels are good or bad, but more about how your levels compare with what is expected for someone your age? Broadly, AMH is higher in your twenties and declines through your thirties, with a steeper drop from the mid-thirties onwards, though there’s wide natural variation, and some people have a lower reserve earlier than expected. AMH results are also assay-specific. Different labs use different testing platforms, and because there’s no single international standard for calibrating AMH, a number from one lab can’t be directly compared to a number from another. This is why a result is only meaningful when it’s read against the reference range of the exact lab that ran it. At Hertility, AMH is interpreted using age-stratified reference ranges, so your result is compared with the expected range for people of a similar age rather than against one universal cut-off. Your result should also be interpreted alongside factors such as your cycle history, symptoms, hormonal contraception, medical history and fertility goals. How does AMH change with age? AMH is generally highest earlier in reproductive life and decreases as the ovarian follicle pool declines with age. There is, however, a lot of variation between individuals. Two people of exactly the same age can have quite different AMH levels without either necessarily having a reproductive health problem. This is why age matters so much when interpreting AMH. AMH also shouldn’t be confused with egg quality. Although both egg number and egg quality decline with age AMH measures the follicle pool. It does not tell us whether the eggs within that pool are chromosomally healthy. What does a low AMH level mean? A low AMH result means your ovarian reserve appears lower than expected for your age. It does not mean that you cannot get pregnant. This distinction is really important. AMH is much better at predicting how your ovaries may respond to fertility medication than it is at predicting whether you will conceive naturally. Current NICE guidance specifically says AMH should not be used to predict the chance of pregnancy through spontaneous conception. Instead, AMH or an antral follicle count (AFC) can be used to predict ovarian response when planning assisted conception. So if your AMH is low, it may mean that fewer eggs would be expected to develop during an IVF or egg-freezing stimulation cycle. Depending on your age and plans for pregnancy, it may also be useful information when thinking about fertility timelines. But it does not tell us whether the eggs you have are healthy, whether you are ovulating, whether your fallopian tubes are open, whether there are any issues affecting your uterus or, where relevant, whether sperm factors could affect conception. Does low AMH mean I can’t get pregnant? Many people with low AMH conceive naturally and without difficulty, particularly when they are younger and their egg quality is high. What low AMH does mean is: It tells you that your egg quantity is lower than average for your age. If your AMH is very low, particularly if you are under 40 and also have irregular or absent periods or symptoms associated with early menopause, your doctor may want to investigate further for conditions such as premature or primary ovarian insufficiency (POI). AMH alone, however, does not diagnose POI. Does high AMH mean I am fertile and won’t have problems conceiving? A high AMH level usually means there are more small follicles in the ovaries than expected for your age. It does not automatically mean you are more fertile. This is another common misconception about AMH. More follicles may mean a larger ovarian reserve, but natural fertility depends on much more than egg quantity. AMH cannot tell you about egg quality, whether you ovulate regularly, the health of your fallopian tubes or uterus, or sperm quality. Higher AMH is also commonly seen in people with PMOS, formerly known as PCOS, because the ovaries often contain a greater number of small follicles. A high AMH result therefore needs context rather than being interpreted as simply “good”. Can AMH diagnose PMOS or PCOS? AMH can contribute to a PMOS/PCOS assessment in adults, but it cannot diagnose PMOS on its own. Under current international guidance, AMH […]

What Is Egg Freezing & Is It Right for Me?
18/08/2022/Zoya Ali BSc, MSc
Egg freezing is a fertility preservation treatment that allows your eggs to be collected, frozen and stored for potential use in the future. You might be considering it because you’d like children one day but aren’t ready yet, you haven’t met the person you want to parent with, or because a medical condition or treatment could affect your fertility. So, what does egg freezing actually do, how successful is it, and how can you decide whether it’s right for you? Quick facts: What is egg freezing? Egg freezing, or oocyte cryopreservation, is a fertility preservation treatment in which eggs are collected from your ovaries, frozen and stored so they can potentially be used in the future. The treatment starts similarly to IVF. Fertility medication encourages several eggs to mature during one cycle. Those eggs are collected during a short procedure and suitable mature eggs are rapidly frozen using a technique called vitrification. If you decide to use them later, the eggs are thawed and fertilised with sperm in a laboratory. Any embryos that develop can then potentially be transferred into the uterus. Modern vitrification has made egg freezing much more effective than older slow-freezing techniques. But there are still several steps between freezing an egg and having a baby. Not every egg survives thawing, fertilises, develops into an embryo or results in a live birth. That’s why egg freezing is best thought of as preserving an option, rather than guaranteeing an outcome. Why do people freeze their eggs? There is no single reason to freeze your eggs. Egg freezing may be worth considering if having a biological child in the future is important to you, but there is a reasonable chance you won’t be ready to try until later, or your future fertility could be affected by a medical condition or treatment. You may know that you’d like children but don’t feel ready to start a family yet because of your relationship, finances, career, health or other circumstances. You may be considering becoming a solo parent in the future, or simply want more time to decide whether parenthood is right for you. This is often referred to as social egg freezing. Egg freezing can also be used for medical fertility preservation, for example before chemotherapy, radiotherapy or some types of ovarian surgery that could affect future fertility. It may also be considered by people at increased risk of reduced ovarian reserve or earlier menopause, or before starting hormone therapy or other gender-affirming treatment that could affect fertility. Egg freezing has become increasingly common in the UK. HFEA data show that the number of patients freezing eggs rose from around 700 in 2014 to 5,580 in 2024, although the number of cycles remained relatively stable between 2023 and 2024. However, having access to egg freezing doesn’t mean everyone needs to do it. The decision should take into account your age, health, reproductive goals, likelihood of delaying parenthood, treatment burden, cost and personal circumstances, rather than being driven by fear or pressure. Egg freezing cannot guarantee a future baby, but for some people it can preserve additional reproductive options for later. What are the benefits of freezing your eggs? The main biological benefit is that egg freezing allows you to preserve eggs at the age you are when they’re collected. Both the number of available eggs and their average reproductive potential decline with age. As eggs age, chromosomal abnormalities become more common, contributing to lower chances of conception and higher miscarriage rates. Once eggs are frozen, the success associated with using them later is strongly influenced by your age when they were collected. That means freezing eggs younger can potentially give you an additional option if you find it difficult to conceive naturally later. For some people, egg freezing can also ease some of the time pressure around family-building decisions. But there is an important trade-off: the earlier you freeze, the greater the chance that you’ll never need those eggs at all because HFEA data shows that while the number of people freezing eggs has risen considerably, the proportion returning to use them remains much lower. However, it is also important to know the limitations. Egg freezing cannot guarantee future fertility. Some frozen eggs won’t survive thawing. Some won’t fertilise. Some fertilised eggs won’t develop into embryos, and not every embryo will result in a pregnancy or live birth. It also doesn’t stop the rest of your body ageing. For example, if you freeze eggs at 30 and use them at 40, those eggs were collected when you were 30. But if they result in a pregnancy, you’ll still be pregnant at 40, so pregnancy-related risks associated with older age can still apply. Egg freezing therefore isn’t a way of “stopping your biological clock”. It’s a way of preserving some of the reproductive potential of younger eggs. How successful is egg freezing? There isn’t one egg-freezing success rate that can accurately tell you your individual chance of having a baby. Success depends on several factors, but two of the most important are your age when your eggs are frozen and the number of mature eggs available when you eventually use them. Age matters because younger eggs are generally more likely to be chromosomally normal. Outcomes are generally better when egg freezing is performed at a younger age, with many fertility specialists considering the late 20s to early 30s an optimal window, although the decision should still be individualised based on your reproductive plans, ovarian reserve and likelihood of using the eggs. Egg number matters because not every egg will progress through each stage of the process. Some eggs won’t survive thawing. Some won’t fertilise. Some fertilised eggs won’t develop into viable embryos. And some embryos won’t implant or result in a live birth. That’s also why there isn’t one magic number of eggs that guarantees a future baby. ASRM states that there isn’t enough evidence to prescribe a universal number of mature eggs that everyone should freeze to achieve a live birth. […]

16 Lifestyle Tips to Help Boost Fertility
27/07/2022/Emily Moreton (Bsc Msc ANutr RN)
If you’re looking to conceive soon, nutrition can have a big impact on your fertility and reproductive health—both positive and negative. Get to know which foods are natural fertility boosters and valuable lifestyle changes that can improve your journey to conception. Quick facts: Why are diet and nutrition important for fertility? As the saying goes, we really are what we eat. Our diets and nutrition impact almost all of our body’s processes—all the way from our metabolism to our mental health. But one often overlooked area is how food can impact our fertility. When trying to conceive, you’ll need a high-nutritional diet. This can increase your chances of conceiving and help to create a healthy home for your baby during their vital first 9 months. Even making small changes to your lifestyle and nutrition choices can go a long way. Here are 16 evidence-backed tips from our Registered Nurse and Associate Nutritionist, Emily Moreton to help prepare your body for pregnancy. You can also book an appointment with a Hertility Nutritionist for a personalised plan. 1. Follow a Mediterranean-style diet Whilst there are no specific guidelines for a recommended fertility diet, the Mediterranean diet, is associated with improved fertility in both women and men. Known for its abundance of fruits, vegetables, nuts, whole grains, fish and healthy fats, the Mediterranean diet is rich in antioxidants. These have been shown to protect sperm and eggs from DNA damage and oxidative stress. A study involving 15,396 participants, which looked at how different diets affect fertility, showed that sticking to the Mediterranean diet improved birth and pregnancy rates significantly, with a 91% higher chance of success. This diet is also high in fibre and rich in vitamins and minerals that support fertility and pregnancy. Think lots of veg, whole grains, nuts, seeds, beans, pulses, olive oils, avocados and oily fish. 2. Eats foods high in antioxidants Eating a diet rich in a variety of colourful fruits and vegetables can provide a wide range of antioxidants that support fertility and overall health. Think making a rainbow on your plate. Foods high in antioxidants include fruits (such as berries, apples, and citrus fruits), vegetables (such as broccoli, spinach, kale, and carrots), nuts, seeds, and whole grains. 3. Increase intake of plant-based proteins In general, you should focus on lowering your intake of red and processed animal meats and focus on adding plant-based protein sources into your diet. This can include fertility-friendly and micronutrient-rich beans, lentils, peas, soya beans, and chickpeas. Plant-based protein sources help to support healthy ovulation and are high in antioxidants and nutrients, such as iron and fibre, which are really important during pregnancy. Low iron levels can add to your tiredness or even could cause iron deficiency anaemia. Iron deficiency during pregnancy can increase the risk of pregnancy complications. It is also important to keep your iron uptake up postpartum too, to replace any iron lost at birth. You’ll also find some protein in whole grains such as quinoa. If you are opting for plant-based meat alternatives (‘fake meats’), choose a brand that is not ultra-processed and low in additives. 4. Cut down on sugar Cutting down on sugar can be beneficial for fertility. This is because too much sugar can lead to insulin sensitivity, disrupting certain reproductive hormones and causing inflammation. Insulin spikes have been associated with poor egg quality and sperm production and could affect implantation. A study published in the American Journal of Clinical Nutrition in 2018 found that women who consumed two or more servings of sugary drinks per day had a 50% higher risk of ovulatory infertility compared to those who consumed less than one serving per month. Reducing sugar intake and opting for a balanced, low-glycemic index diet can help improve insulin sensitivity and overall reproductive health. Limit sugary foods and high glycemic index foods such as cakes, biscuits, fizzy drinks, energy drinks, sweets, white rice and white bread. Check the labels for high sugar content. 5. Take pregnancy supplements Folic acid Folic acid is an important supplement during pregnancy because it decreases a risk called neural tube defects. This is a defect that can occur during the development of the baby’s brain and spine. If you are currently trying to become pregnant, it is advised to take at least 400 mcg of folic acid supplement every day for 12 weeks before conception and for at least three months after conceiving. Some people are at an increased risk of their baby having a neural tube defect and so it is advisable to speak with your doctor as they may recommend and prescribe you a higher dose. Prenatal vitamins Prenatal vitamins typically contain a combination of various vitamins and minerals that are important for both maternal and foetal health. While folic acid is a main component of prenatal vitamins, these vitamins usually contain a range of other nutrients as well. These include iron, calcium, vitamin D and other essential vitamins and minerals needed to support maternal health and the baby’s development during pregnancy. Tip: More often than not, doctors will suggest taking prenatal vitamins instead of just folic acid supplements because they cover a wider range of needs for both mum and baby’s health. However, it’s essential to consult with your doctor to determine the most appropriate approach for your unique needs. 6. Take Vitamin D for pregnancy A previous study has shown that both men’s and women’s vitamin D levels impact fertility and IVF results. It showed that Vitamin D supplements reduce risks for mums and babies, might prevent bone problems, and play a role in foetal development. How much Vitamin D should I take? It’s recommended that all adults at all stages of life should supplement with 10 micrograms a day of Vitamin D, in the UK. This is particularly true if you are trying to conceive, or you are pregnant—so be sure to supplement right through from the preconception period to breastfeeding. Prenatal vitamins often contain vitamin D, but the amount can vary […]

Why Should I Test My Hormones?
05/07/2022/Zoya Ali BSc, MSc
Hormones help to regulate almost all of the body’s processes, including reproductive health and fertility. Testing your hormones regularly can give you insights into your overall health and help you track changes in your menstrual cycle and fertility over time. Here we’ve broken down which hormones you should test and why. Quick facts: What are hormones? Put simply, hormones are small chemical messengers that travel through the blood to different parts of your body. They help control many different functions from growth and development to metabolism, the menstrual cycles, fertility and mood, just to name a few. Hormones are made by special cells in the endocrine system. Some of the major endocrine glands are: Why are sex hormones important? Sex hormones are a group of hormones that help to regulate the female and male reproductive organs and fertility. They are important not only for reproductive health but for overall health too—often having multiple functions within the body. The main hormones involved in the female reproductive system are: Thyroid hormones can also impact your levels of reproductive hormones. Why do you need to test your hormones? Hormones are often involved in complex feedback loops with one another. This means if one hormone gets off balance, it can often disrupt the whole system and bring about multiple, often overlapping symptoms. Our hormones are also changing constantly, as we age and in response to things like lifestyle factors, medications or external stresses. A change in your hormone levels could be the reason you’re feeling sluggish or slightly emotional, explain your irregular periods or why you’re struggling to get pregnant. Our hormone levels can give us insight into both our overall reproductive health, show our risk factors for certain conditions, explain any unwanted symptoms, or indicate the health of our ovarian reserve and fertility. Which hormones should I test? Which hormones you need to test and monitor will depend on your individual medical history, symptoms, biometrics and fertility goals. Luckily, our Online Health Assessment is built on a proprietary algorithm that does the leg work for you, recommending you hormone panel personalised to you. Let’s take a look at each of the main female sex hormones and what testing them could tell you. Follicle-stimulating hormone One of the main hormones that regulate the menstrual cycle and fertility is follicle-stimulating hormone (FSH). Its main job is to stimulate your ovaries each month to mature a set of follicles (the sacs that house the immature eggs) into mature eggs. If FSH gets out of balance, ovulation can be affected, negatively impacting fertility and causing irregular cycles. FSH levels increase with age. High FSH is usually an indication that ovarian reserver is declining and more FSH is needed to encourage your eggs to grow. This is why monitoring FSH can help you understand the health of your ovaries. FSH levels will slowly increase with age as your ovarian reserve declines. When your ovarian reserve is finally depleted (and menopause occurs), FSH levels become substantially elevated. This is why FSH is used as an indicator of menopause. Persistently high FSH levels in someone younger than 40, along with irregular periods and vasomotor symptoms, could indicate premature ovarian insufficiency (POI). This is when someone experiences menopause before the age of 40. FSH levels are usually not recommended as an indicator of menopause beyond the age of 45. Oestrogen (Oestradiol) Oestrogen is an important hormone for the growth and maturation of eggs and the thickening of the uterus lining each cycle. It’s also incredibly important for overall health, regulating bone, heart, skin and hair health, as well as mood. Oestrogen is made by the ovaries, so monitoring oestrogen levels gives a good indication of how well your ovaries, and menstrual cycle in general, are functioning. Oestrogen levels will fluctuate and eventually significantly drop when your ovarian reserve becomes depleted and menopause occurs. Low oestrogen levels are therefore linked with many symptoms of menopause, such as dry skin and hair, vaginal dryness, hot flushes, brain fog, night sweats, difficulty falling asleep and fatigue. Luteinising hormone (LH) LH is the hormone responsible for triggering ovulation, which is the release of the mature egg from an ovary each month. If your LH levels are too low or too high, it can interfere with ovulation. High LH levels are often seen in those with Polyendocrine Metabolic Ovary Syndrome (PMOS, formerly known as PCOS), which can cause irregular ovulation and issues with periods and fertility. Anti-Müllerian hormone (AMH) Anti-Müllerian Hormone (AMH) is a super important hormone for fertility and overall reproductive health. AMH is made by the small sacs, called follicles, in your ovaries. These follicles house your eggs. Since AMH is made by the follicles, your AMH levels can therefore give you an insight into your ovarian reserve, or how many eggs you have at the time of testing. We were all born with all of the eggs we’ll ever have, and as we age, both our egg quality and quantity decline. Generally, our AMH levels will decline with age as our egg count diminishes, unless we have an underlying condition or lifestyle factor which is affecting our AMH levels (like PMOS). High AMH levels can be an indicator of polycystic ovaries and can be used to diagnose PMOS based on recently updated clinical guidelines. On the other hand, low AMH along with high FSH and low oestrogen is usually an indicator of low ovarian reserve. AMH is often also used to predict someone’s chances of success during fertility treatment, such as egg freezing and IVF. However, it’s important to remember that AMH can only tell you about the quantity, and not the quality, of your eggs. Testosterone Testosterone can be converted to produce the wonder hormone oestrogen and is also associated with libido, maintaining muscle mass, vaginal health, breast health and bone health. High levels of testosterone can cause symptoms such as excess body and facial hair, acne, and irregular or absent periods. These symptoms are often seen in women with PMOS […]

Support employees going through fertility treatment with fertility benefits
20/05/2022/Zoya Ali BSc, MSc
Still, a hushed and taboo topic – almost 1 in every 6 couples have fertility issues in the UK-that’s about 3.5 million. The global infertility rate is increasing as people choose to have children later in their lives, with the average age to have a first child now 30.7 years in the UK. This means that fertility treatment is becoming more and more common, so the need for fertility benefits as support is more important than ever. Infertility and the fertility treatment journey can be a roller coaster, both emotionally and physically. Almost 90% of people experience depression as a result of infertility. Over 40% do not disclose that they are undergoing fertility treatment to their employers fearing that it would negatively impact their career prospects. Here are a few recommendations on how you can support your employees undergoing fertility treatment and challenges better: 1. Help people understand the basics about their fertility. Up to 59% of respondents in a Fertility Network UK survey felt their employer would benefit from education about fertility and treatment options to help better understand and support the needs of someone undergoing treatment. Referring your employee to resources that may help them understand the basics of all things reproductive health will make them more confident in their reproductive journeys. 2. Help establish the feeling of a supportive environment. Educational workshops can be a stepping stone to understanding the concerns your employees might have surrounding their fertility. These can help build open dialogue and encourage them to discuss fertility issues without concerns of negative consequences. 88 % of employees who felt unsupported during IVF treatment have left or consider leaving their job. Partnering with organisations that provide fertility counselling can support your employees during this emotional turmoil. 3. Establish a fertility benefits policy in the workplace. Eligible employees in the UK have a statutory right to up to 52 weeks of maternity leave and 2 weeks paternity leave. On the other hand, preconception care is not a statutory right, which is why most employers do not have formal policies in place. With the number of NHS-funded cycles declining rapidly and extensive criteria couples, especially LGBTQ+ couples, have to fulfil before accessing a funded cycle, many people are opting for private treatment but few can afford it. The average cost per cycle in a private clinic is about £5,000+, but it can cost even more depending on the treatment options chosen and the clinic. Establishing fertility benefits policies – covering proactive fertility testing, fertility treatment or egg freezing costs or providing low-interest loans – can help align your interests with your employees, supporting their individual journeys to parenthood, facilitating equality, diversity and inclusion. 4. Establish flexible work options. Fertility treatment is time-consuming because it means having to attend multiple tests, appointments, consultations and procedures. Appointments can often end up with long wait times or need recovery time. For most people, a single cycle of IVF can take between four and six weeks. Usually, the time employees take off work for fertility treatment is deducted from their paid time off or sick leave. Not having a fertility treatment leave policy has been linked to greater levels of distress, risk of burnout and reduced performance. Providing flexible working hours and arrangements can help support employees with the time they might need to attend clinic appointments. 5. Find the right partner to support with fertility benefits. Selecting the optimal partner is paramount when developing and implementing employee reproductive health benefits. To ensure your workforce receives the most comprehensive support possible, the chosen solution should address the full spectrum of the fertility and hormone journey. A truly comprehensive benefit package should aim to integrate several critical components: Hertility Health is dedicated to shaping the future of Reproductive Health, providing individuals with the tools to understand and manage their fertility and hormone health from menstruation through menopause. To learn more about implementing our Reproductive Health Education and Benefits within your organisation reach out to: benefits@hertilityhealth.com or visit our website: https://hertilityhealth.com/workplace.

How is period pain impacting your employees?
20/05/2022/Zoya Ali BSc, MSc
Absenteeism, presenteeism, and stigma in the workplace. The profound impact of menstruation on workplace productivity and attendance is often overlooked, but period, PMS and symptoms associated can be extremely debilitating. Every day, millions of people show up to work and perform at the highest level while silently navigating the complexities of reproductive health. Many might try to manage it with home remedies and over the counter medication; for up to 1 in 10 women, it can cause severe debilitating chronic pain, impacting their daily routine due to a condition called endometriosis. “I never did say to work, that I was off because of period pain because I worked for years in a very male dominated banking environment…I felt there was an issue of stigma with saying I was off…I would have to invent reasons month after month, soldier on, dose yourself up and try and get through the days best you could. Then collapse when you go home.” – (Gender Health Gap Report, 2024) The Data: How can employers support this? 1. Help people understand the basics of their reproductive health. A supportive workplace can improve employee productivity and loyalty, reduce absenteeism and improve DE&I. Here are a few recommendations on how you can support your employees better through inclusive healthcare. Many women grew up believing period pain was a normal part of life. Social and cultural taboos combined with a lack of education on menstrual health could explain why someone might not discuss their period-related symptoms or ignore them altogether. Employers can help break this cycle of misinformation by referring employees to resources to understand their reproductive health better. Additionally, organising lunch & learns and workshops can be a stepping stone to open dialogue and normalise conversations around period pain in the workplace. 2. Establish support in the workplace. Experiencing pain in the workplace is challenging for employees. Providing flexible working hours, rotas and arrangements such as a quiet room, period products, heat packs, or modified workstations can support employees with the time they might need to prioritise their health. Research on menstrual workplace policies from Monash University found that flexible policies based on the individual employee’s needs were more effective than a blanket period leave. Beyond policies, ensuring that managers are well-trained to talk about reproductive health and support employees through their struggles will also help create a supportive environment at work. 3. Find the right partner to support reproductive health policies. Taking the first steps in making the workplace more period-friendly is a big task, which is why it is important to find a reputable expert provider who can support employers in educating their workforce, instating progressive policies and providing solutions to employees’ worries around their reproductive health. Hertility Health is shaping the future of reproductive health by giving women the ability to understand and manage their hormone health from menstruation to menopause. We believe in a proactive approach to reproductive health – by detecting issues early, helps prevent issues later down the line. We deliver our world-class reproductive health benefits to many leading companies and improve access to reproductive healthcare and education. We provide in personalised plans – for you and your employees – and offer a range of corporate plans and coverage options to suit your needs, from educational workshops, to female health assessments and consultations with in-house experts. For early adopters that have existing fertility treatment benefits for employees, we help you protect your budget – our proactive hormone tests are a fraction of the clinic price and by identifying issues early we can prevent costly treatment. Where treatment is required, our blood tests are accepted by partner clinics and reduce time to treatment. We provide DE&I impact reports, so you can see the tangible impact on your workforce and your bottom line. To learn more about our Reproductive Health Education and Benefits for Employers, reach out to benefits@hertilityhealth.com or visit our website https://hertilityhealth.com/workplace

Why should reproductive health be a part of your mental health benefits?
20/05/2022/Zoya Ali BSc, MSc
COVID-19 and the shift to remote working has catalysed the demand for mental health benefits – it is now a “must have” for employers in 2021. In fact, in a recent survey, 91% of respondents stated that a company’s culture should support mental health. It is no coincidence that mental well-being is included in how reproductive health is defined by the World Health Organisation, stating that “Reproductive health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity, in all matters relating to the reproductive system and to its functions and processes”. These two elements of well-being are interconnected. As a result, it is impossible to provide comprehensive mental health benefits without considering the impact that reproductive health conditions can have and figuring out how employees dealing with those can be supported. How do reproductive health conditions affect mental health? InfertilityTake infertility, which affects 1 in 6 couples in the UK. Despite its prevalence, it is often met with confusion and denial.. This can seriously impact mental well-being – feelings of anxiety, depression and loss are all common. Besides, treatment can be time-consuming, stressful and a significant financial burden for individuals. Leading employers in the benefits space are recognising the impact that infertility may have on mental health and offering “fertility leave” as well as compassionate leave after miscarriage. EndometriosisReproductive health conditions such as endometriosis are associated with difficulty conceiving and chronic pain, both of which impact quality of life. Alongside having increased sick leave and loss of productivity, women with endometriosis feel their career goals were impacted negatively. Premenstrual syndrome (PMS)PMS describes the array of physical and emotional changes that occur as part of the monthly cycle. Approximately 90% of people who menstruate experience PMS. In some cases, this can be debilitating, a condition known as premenstrual dysphoric disorder (PMDD). PMDD can be so severe that suicidal thoughts are common in these women. Undiagnosed health issuesUnfortunately, it is not just the physical manifestations of the conditions alone that may impact employees’ mental health. Stigma and shame on reproductive health conditions from society and inadequate support from healthcare with symptom dismissal and months or years required to get to a diagnosis can be a significant cause of anxiety or depression for people suffering from a reproductive health condition. Many things in this journey even after getting the answers are outside of employees’ control. There are no guarantees that fertility treatments will succeed; failed attempts can seriously affect mental health, especially in those cases where little can be done to change the outcome. How can you support your employees on their reproductive health journey?There are several things that you can do to help alleviate the burden reproductive health conditions can place on mental health. Destigmatise reproductive health conditions by encouraging education and learning. This is a great way to challenge the current attitude to reproductive health conditions in the workplace and facilitates supportive conversations. Joining schemes provided by charitable bodies such as the Endometriosis Friendly Employer scheme can help you to make those first steps. Create a supportive workplace environment through flexible working hours for those who need to attend multiple appointments, inclusive leave policies and offering free menstrual products in bathrooms. Provide comprehensive reproductive health benefits by partnering with companies like Hertility to connect your employees to expert care and help them make informed decisions with regards to their reproductive health. These can include things such as proactive testing opportunities with actionable insights, fertility counselling, referrals to trusted clinics and specialist care with experts in the field. About Hertility HealthHertility Health is shaping the future of Reproductive Health by giving women the ability to understand and manage their fertility and hormone health from menstruation to menopause. 1 in 3 women suffer from a reproductive health issue, yet conversations around fertility, menopause and menstrual symptoms are still stigmatised in the workplace. As employees suffer in silence – up to £4k is lost per year per employee due to reduced productivity, absenteeism and presenteeism. Hertility reduces the need for unnecessary appointments and delay in diagnosis time through an online health assessment and at home test. To learn more about our Reproductive Health Education and Benefits for Employers, reach out to benefits@hertilityhealth.com or visit our website.

How to support LGBTQ+ employees
20/05/2022/Zoya Ali BSc, MSc
Deciding to start a family is never an easy process, but for some employees who identify as part of the LGBTQ+ community, their journey to parenthood might need some more support. Being a 21st-century employer means establishing an inclusive, progressive and supportive work environment to attract and retain employees. A 2017 study by Mercer found that 33% of UK respondents do not offer equal benefits to LGBTQ+ employees because they do not know how to implement such a benefit! Check your fertility Here are some ways to provide support to your LGBTQ+ employees in their fertility journeys Recognise that there are multiple paths to parenthood Partner with experts like Hertility to raise awareness about the advances in fertility treatments such as IVF (in vitro fertilisation), IUI (intrauterine insemination), surrogacy, etc., that made it possible for LGBTQ+ couples to have biologically related children. Refer your employee to resources like Hertility that may help them understand the basics of all things reproductive health will make them more confident in their reproductive journeys. Don’t treat fertility treatment as a lifestyle choice Gender-affirming treatments can impact fertility, and therefore, many require fertility preservation, such as banking eggs, sperm or embryos before medical transition. With the number of NHS-funded cycles declining rapidly, LGBTQ+ couples have to fulfil extensive criteria before being eligible for a funded cycle, because of which, many are opting for private treatment, where the average cost per cycle can be about £5,000, varying significantly depending on the treatment options chosen and the clinic (HFEA). Listen to feedback from employees, ask them what they would want to feel more supported in their choices and try to develop policies around them. Establishing fertility benefits policies – covering proactive fertility testing, fertility treatment or egg freezing costs or providing low-interest loans – can help align your interests with your employees, supporting their individual journeys to parenthood, facilitating equality, diversity and inclusion. Ensure you have fertility leave policies and make sure they are inclusive If you have existing family planning and health benefit policies, revisit the language and clauses to ensure LGBTQ+ employees are eligible for the equal benefits to support them as they embark on their parenthood journey, whether that be through fertility treatment, surrogacy, adoption, or parental leave. Hertility can help train your staff on all things related to policies. About Hertility Health Hertility Health is shaping the future of Reproductive Health by giving women the ability to understand and manage their fertility and hormone health from menstruation to menopause. 1 in 3 women suffer with a reproductive health issue, yet conversations around fertility, menopause and menstrual symptoms are still stigmatised in the workplace. As employees suffer in silence – up to £4k is lost per year per employee due to reduced productivity, absenteeism and presenteeism. To learn more about our Reproductive Health Education and Benefits for Employers, reach out to benefits@hertilityhealth.com or visit our website. Trusted resources: https://www.imercer.com/uploads/dmi/2017_lgbt_sample.pdf https://www.bpas.org/media/3484/bpas-fertility-investigation-nhs-funded-fertility-care-for-female-same-sex-couples.pdf

Testosterone 101: Understanding Your Testosterone Levels
06/10/2021/Zoya Ali BSc, MSc
Testosterone is an important androgen hormone in people of all sexes. In this article, we’ll cover exactly what it does in the body, what the symptoms and causes of high or low testosterone are and how you can ensure your levels are balanced and healthy. Quick facts: What is testosterone? Testosterone is an important hormone for regulating sex drive (libido), bone and muscle mass and fat distribution. It’s part of a group of hormones called androgens. There are a lot of misconceptions about testosterone being just a “male” hormone. Whilst testosterone plays an important role in the development of the male sex organs and male secondary sex characteristics, people of all sexes have testosterone. Everyone produces and requires a certain amount of androgen hormones for reproductive development. The difference is just how much testosterone we have based on our sex-at-birth. How is testosterone made? In women and people assigned female-at-birth, testosterone is produced by the ovaries and adrenal glands. It’s then converted to hormone–oestrogen. Testosterone production is age-dependent and it gradually declines with age. Most of the testosterone in the body is inactive. It remains bound to a protein called, sex hormone-binding globulin (SHBG). The small amount of testosterone that’s unbound and therefore active, is called freely circulating testosterone (free T). Free T can enter cells to bring about its effects. Our free T levels are affected by the levels of SHBG. Low levels of SHBG result in higher free testosterone, whereas high levels of SHBG result in lower free testosterone. What does testosterone do in the body? Some of the functions of testosterone are: What are the symptoms of high testosterone? Excess levels of testosterone in the body is called hyperandrogenism. This can bring about symptoms like: Some studies suggest that high testosterone levels may increase the risk of developing high cholesterol, heart disease and type 2 diabetes. What causes high testosterone levels? The most common causes of high testosterone levels are underlying health conditions. It can also be caused by certain medications and lifestyle factors. Let’s look at the main ones… PMOS (formerly PCOS) Polyendocrine Metabolic Ovary Syndrome (PMOS, formerly known as PCOS) is a hormonal and metabolic condition affecting 1 in 10. The exact cause is still being researched, however, the proposed causes include an excess of androgens and insulin, genetic and environmental factors. If you suspect you might have PMOS, our at-home tests can give you a better insight into your hormones. Congenital andreal hyperplasia Congenital adrenal hyperplasia (CAH) is an inherited condition that affects the adrenal glands. These are small glands located on top of the kidney. They produce hormones like cortisol (stress hormone), dehydroepiandrosterone (DHEA) and testosterone. People with CAH are unable to produce an enzyme necessary to regulate the production of these hormones, which can result in an overproduction of testosterone. It’s been found to be more common in some ethnic groups such as people of Hispanic, Mediterranean, Yugoslavian and Ashkenazi Jewish descent. Cushing’s syndrome is another hormonal condition impacting the adrenal glands. It results in excessive cortisol and androgen production. Medications Testosterone levels can rise due to certain medications, such as: Alcohol Excessive alcohol consumption may increase levels of testosterone in premenopausal women, however, research is conflicting. How to lower my testosterone levels? Treatment for high testosterone depends on the cause, but generally, it is a combination of lifestyle changes and medications. Achieving a healthy weight by including a healthy balanced diet and exercise routine may help with the symptoms of a hormonal balance. Medications used to treat high testosterone, and associated symptoms include: What are the symptoms of low testosterone? If you’re experiencing low testosterone, you may experience some of the following symptoms: Low testosterone over a long period may also contribute to long-term health conditions such as heart disease, memory issues and loss of bone density. Often, the symptoms of low testosterone in women are undiagnosed or misdiagnosed. Some of the conditions that low testosterone may be mistaken for include stress, depression and the side effects of menopausal changes in women. What could cause low testosterone levels? The most common causes of low testosterone levels are often age, underlying conditions and problems with certain glands. Age Testosterone levels naturally decrease as we age. As it’s produced in the ovaries, the natural decrease in ovarian function with age means that some may experience low testosterone levels as they transition from the perimenopausal phase into menopause. Underlying health conditions Premature ovarian insufficiency (POI) can increase your risk of low testosterone. Additionally, surgery, such as the removal of the ovaries, can cause lowered testosterone levels. Problems with the hypothalamus or pituitary gland Underlying health conditions impacting the pituitary, hypothalamus, or adrenal glands can also cause lowered testosterone levels. This is because these parts of the brain are responsible for the secretion of hormones which control the proper functioning of the ovaries. A disruption in the pituitary gland can also impact the adrenal gland. Addison’s disease or adrenal insufficiency is a hormonal condition that occurs due to underactive adrenal glands and can cause a low level of its hormones. What can I do to increase my testosterone levels? Low testosterone levels effects and treatments in women are still being researched and treatment is usually recommended only if symptoms are significantly impacting health and quality of life. Testosterone replacement therapy is a form of hormone replacement therapy (HRT) based on the replacement of testosterone. It may be prescribed orally, as injections, gels or skin patches. DHEA is a precursor to testosterone, and it is believed that taking DHEA supplements could increase the amount of testosterone. It is always recommended to speak with a doctor before starting any medication or supplements. How to test testosterone levels? If you’re experiencing any of the symptoms mentioned above, our Advanced At-Home Hormone and Fertility Test can determine your testosterone levels. Hormone testing is the only way to know what your testosterone levels are for definite. Our Doctors can recommend a care plan for you, based on your symptoms, hormone […]





